Found 91 matching trials
Precision Medicine in the Depression Treatment N/A The BrainDrugs-D study uses multimodal neuroimaging combined with self-repo...
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Neurobiology Research Unit, Rigshospitalet
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Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression PHASE2 Background:
Major depressive disorder (MDD) is a serious mental illness th...
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National Institutes of Health Clinical Center
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Precision Psychiatry for Depression: Immune Response and Affective Symptoms as Predictors of Response to Antidepressants N/A Objectives: To identify in patients with major depression different periphe...
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Hospital Universitari Germans Trias i Pujol
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Does Dual Therapy Hasten Antidepressant Response? PHASE4 This study will utilize a randomized double-blind design to evaluate whethe...
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New York State Psychiatric Institute
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Mechanisms of Antidepressant Non-Response in Late-Life Depression NA This project seeks to elucidate the mechanisms by which antidepressant medi...
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New York State Psychiatric Institute
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Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients NA The purpose of this study is to determine whether alteration of signal tran...
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Samsung Medical Center
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Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine PHASE1 The Investigators are conducting a research study to learn about the safety...
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Centre for Addiction and Mental Health
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Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis) NA BACKGROUND: Lumbar spinal stenosis - known by patients as "arthritis of the...
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UPMC Shadyside Center for Integrative Medicine
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A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression PHASE2 This study is open to adults with depression (major depressive disorder) fo...
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University of Alabama at Birmingham
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A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression PHASE3 The purpose of this study is to compare the efficacy and safety of switchin...
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Multiple Locations
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